Kuano / Science, connected

Molecular understanding.
New possibilities for discovery.

Kuano combines quantum physics-based molecular design with an agent-enabled scientific platform for drug discovery and molecular innovation.

We work with small biotechs and chemistry discovery teams, pharmaceutical companies, CROs and other R&D organisations, from focused scientific questions to broader programmes and integrated capabilities.

For your programme

Advance a programme.

Resolve molecular questions and develop useful chemistry, connecting scientific expertise with your existing evidence.

Explore programme collaboration

For your organisation

Build a capability.

Access selected Kuano tools and workflows, or work with us to develop scientific infrastructure within your organisation.

Explore the platform

Partnerships

Work with Kuano.

Scientific collaboration, selected capabilities, infrastructure and joint offerings.

Explore partnerships

Where we contribute

What would progress look like for you?

  1. Make sense of the evidence.

    You have compounds and experimental results, but important questions about models, binding or mechanism remain. Connect that evidence to interpretations you can test.

  2. Open a new design direction.

    Your programme needs differentiated chemistry or a better explanation of molecular behaviour. Use scientific insight to guide the next designs and experiments.

  3. Establish repeatable capability.

    Your teams need to apply scientific methods across projects. Bring tools, data and computation into coordinated workflows, with a deployment approach suited to your organisation.

The Kuano platform

Scientific methods, computation
and evidence, connected.

Kuano scientists use the platform in their own work. It also provides a foundation for selected capabilities and infrastructure developed with clients.

Quantum Lens holds the scientific methods and workflows. Compute runs the work; the Database retains chemistry, context and experiment provenance.

Agentic orchestration layer

Software agents coordinate steps across scientific tools, Compute and the project record, under scientist direction and review.

Our aim is to help specialist expertise support more programmes while making methods and analysis easier to share across discovery teams. Scientists retain control over assumptions and interpretation.

Scientific evidence

From mechanism to molecular insight.

Design followed by experimental testing

Experimentally tested chemistry

DNMT1

Mechanistic insight informed new inhibitor chemistry, followed by experimental assessment.

Read the case

Mechanistic design & testing

NOTUM

A transient reaction feature informed molecular design and experimentally tested inhibitor chemistry.

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Interpretation of existing evidence

Retrospective analysis

JAK3

Quantum analysis examined covalent behaviour in the protein environment using published ligands.

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Scientific focus

Understand the molecule.
Explore the design possibilities.

01

Enzyme mechanisms

Investigate reaction pathways and transition states to identify opportunities for molecular design.

02

Covalent design

Examine reactivity alongside binding geometry and the molecular environment.

03

Selectivity

Understand why related compounds or targets behave differently, and use that insight to guide design.

04

Binding and difficult pockets

Explore molecular dynamics, candidate binding sites and structural hypotheses against available evidence.

Research & updates

Explore the work behind the science.

Read selected publications, funded research and company updates.

Explore publications and funded projects

Kuano joins the pharma and AI conversation at Life Sciences Week

Vid Stojevic joined a Birmingham panel exploring how pharma and AI companies can build effective partnerships.

Read the update

Kuano demonstrates its agent-supported platform in Singapore

At Asia Bio Partnering Forum, Kuano showed how its agent-supported platform can help plan, run and analyse a computational study.

Read the update Watch the demo

Kuano at BIO International Convention in San Diego

Kuano joined the global biotech community in San Diego for discussions on computational approaches to drug discovery.

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From discussion to demonstration: agentic AI in drug discovery

Our King’s Cross event brought together perspectives from pharma, AI, chemistry and investment, alongside a Kuano demonstration of covalent binder design workflows.

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Kuano in MedNous! Redefining Drug Discovery with the Quantum Lens

Kuano in MedNous! We’re thrilled to be featured in this month’s edition. You can read the article entitled ‘Redefining Drug Discovery using Quantum Physics’. At Kuano, we’re bringing quantum…

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Kuano at Discovery On Target in Boston

If you missed Kuano’s poster at Discovery On Target in Boston last month, it is now available on our website here.

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Work with Kuano

Start with the outcome you need.

A contribution shaped around your team.

Agree the scientific question, resources and responsibilities. Work alongside your own specialists and experimental partners, with scope to develop the collaboration as the evidence grows.